2008•International Journal of Pathology and Clinical MedicineRequires access

Progression of adipocyte fatty acid binding protein

Jie Wu

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Abstract

Fatty acid-binding proteins(FABP) belong to a family of low-molecular-weight cytoplasmic protein,and adipocyte fatty acid binding protein(A-FABP/ aP2) is one of the members of the family.A-FABP binds saturated or unsaturated long-chain fatty acids reversiblely,facilitate trafficking and maintain metabolism equilibrium,regulate the production of lipid and lipolysis.Research in recent years shows that biological reaction of A-FABP plays an important role in lipid metabolism and various diseases.The relationship is especially close between A-FABP and metabolic syndrome,atherosclerosis.

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What this paper is about

Fatty acid-binding proteins(FABP) belong to a family of low-molecular-weight cytoplasmic protein,and adipocyte fatty acid binding protein(A-FABP/ aP2) is one of the members of the family.A-FABP binds saturated or unsaturated long-chain fatty acids reversiblely,facilitate trafficking and maintain metabolism equilibrium,regulate the production of lipid and lipolysis.Research in recent years shows that biological reaction of A-FABP plays an important role in lipid metabolism and various diseases.The relationship is especially close between A-FABP and metabolic syndrome,atherosclerosis.

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Available abstract

Fatty acid-binding proteins(FABP) belong to a family of low-molecular-weight cytoplasmic protein,and adipocyte fatty acid binding protein(A-FABP/ aP2) is one of the members of the family.A-FABP binds saturated or unsaturated long-chain fatty acids reversiblely,facilitate trafficking and maintain metabolism equilibrium,regulate the production of lipid and lipolysis.Research in recent years shows that biological reaction of A-FABP plays an important role in lipid metabolism and various diseases.The relationship is especially close between A-FABP and metabolic syndrome,atherosclerosis.

Key concepts: Fatty acid-binding protein, Lipolysis, adipocyte protein 2, Adipocyte, Fatty acid, Biochemistry, Lipid metabolism, Lipid droplet

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