Research progress on the mechanism of tumor immune escape
Yan Yong-zhe
Abstract
Yan Yong-zhe
Abstract
Tumor cells generated occasionally in the body can be identified and removed as a foreign body by immune cells.The generation,development and metastasis of tumor cells although under the body′s immune surveillance,suggest that the tumor cells have the capability of immune escape.In this paper,the research progress of tumor immune escape in the process of tumor immunity including tumor antigen expression,identification,processing,presenting,T cell proliferation,activation and differentiation,as well as the emergence of immune effect is reviewed.
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Tumor cells generated occasionally in the body can be identified and removed as a foreign body by immune cells.The generation,development and metastasis of tumor cells although under the body′s immune surveillance,suggest that the tumor cells have the capability of immune escape.In this paper,the research progress of tumor immune escape in the process of tumor immunity including tumor antigen expression,identification,processing,presenting,T cell proliferation,activation and differentiation,as well as the emergence of immune effect is reviewed.
Key concepts: Immune system, Immune escape, Mechanism (biology), Biology, Tumor cells, Immunity, Immune surveillance, Immunology