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Dynamic change of blood coagulation in SIRS patients

Xiaojuan Zhao

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Abstract

Objective To investigate the blood coagulation disorder in SIRS patients. Methods Sixty-four patients were divided into mild,severe and dead groups. All patients’AT-Ⅲ,t-PA,PAI,GMP-140 and P-selection were measured on 0,2,4 and 6 days after admission. Results The coagulation and fibrinolysis were activated,and fibrionolysis was inhibited. There was a significant difference between survivors and dead group(P0.01).These changes were closely correlated with the APACHE-Ⅱ score. Conclusion Change in coagulation parameters is important for evaluating the condition and prognosis of SIRS patients.

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What this paper is about

Objective To investigate the blood coagulation disorder in SIRS patients. Methods Sixty-four patients were divided into mild,severe and dead groups. All patients’AT-Ⅲ,t-PA,PAI,GMP-140 and P-selection were measured on 0,2,4 and 6 days after admission. Results The coagulation and fibrinolysis were activated,and fibrionolysis was inhibited. There was a significant difference between survivors and dead group(P0.01).These changes were closely correlated with the APACHE-Ⅱ score. Conclusion Change in coagulation parameters is important for evaluating the condition and prognosis of SIRS patients.

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Available abstract

Objective To investigate the blood coagulation disorder in SIRS patients. Methods Sixty-four patients were divided into mild,severe and dead groups. All patients’AT-Ⅲ,t-PA,PAI,GMP-140 and P-selection were measured on 0,2,4 and 6 days after admission. Results The coagulation and fibrinolysis were activated,and fibrionolysis was inhibited. There was a significant difference between survivors and dead group(P0.01).These changes were closely correlated with the APACHE-Ⅱ score. Conclusion Change in coagulation parameters is important for evaluating the condition and prognosis of SIRS patients.

Key concepts: Coagulation, Fibrinolysis, Medicine, Internal medicine, Coagulation Disorder, Gastroenterology, Systemic inflammatory response syndrome, Sepsis

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