Application of CT Perfusion in Cerebral Ischemic Infarction

Objective To evaluate the diagnostic value of CT perfusion in cerebral ischemic infarction. Methods First pass,single section perfusion CT was performed in 15 patients who presented with symptoms of acute stroke onset between 5 and 20 hours. Single section perfusion CT scans were obtained immediately after the nonenhanced CT study in interested section. Results For 4/15 cases, ischemic lesions were found on both conventional CT and CT perfusion image after 12 hours onset of stroke,6/15 patients had negative results on conventional CT less 12 hours but positive on CT perfusion, three parametric images showed the lesions hypoperfusion,the lesions itself showed MTT delay,CBF and CBV decrease. 5/15 cases had negative results on both conventional CT and CT perfusion. Conclusion Perfusion CT is potentially useful for detecting cerebral perfusion deficits in acute ischemic stroke before morphologic changes are observable on native CT scans.