Effect of Supplementing Qi and Nourishing Yin on Gastrointestinal Reactions and Quality of Life in Patients with Advanced Lung Cancer after Chemotherapy

Objective:To observe the effect of supplementing qi and nourishing yin on gastrointestinal reactions and quality of life in patients with advanced lung cancer after chemotherapy.Method: Eighty-five patients with advanced lung cancer were randomly divided into treatment group(n=45)and control group(n=40).The treatment group was given remedy of supplementing qi and nourishing yin combined with chemotherapy.The control group was given chemotherapy.A treatment cycle was four weeks.The traditional Chinese medicine(TCM) clinical symptoms,KPS score,body weight,quality of life in each group before and after treatment were observed in two cycles.Result: In the two groups,the symptom scores were improved after the treatment cycle(P0.05).The treatment group could relieve the lung cancer clinical syndromes including cough,bloody sputum,chest pain,shortness of breath and fatigue better than control group(P0.05).The treatment group could significantly relieve syndromes of nausea and vomiting,loss of appetite,constipation,improving the quality of life and body weight comparing to control group(P0.05).Compared with the control group,the physical condition and functional status of the patients in the treatment were better(P0.05).As side effects and toxicity concerned,the results were similar in two groups.Conclusion: As for the advanced lung cancer patients of chemotherapy with cisplatin,the use of supplementing qi and nourishing yin decoction can not only improve the symptoms of lung cancer,but also effectively reduce gastrointestinal reactions induced by chemotherapy and improve patient's quality of life.