The Clinical Application of TCT,Colposcopy and LEEP in Cerical Intraepithelial Neoplasia

Objective:To investigate the clinical value of TCT,colposcopic biopsies and LEEP in diagnosis and treatment of cervical intraepithelial neoplasia.Method:The clinical data of 106 patients with cerical intraepithelialneoplasia diagnosed with TCT and colposcopic biopsy in our hospital from January 2011 to December 2011 were retrospectively analyzed.All patients were treated with LEEP.Three cases of them with CIN-Ⅲ received extra fascial hysterectomy resection besides LEEP.The postoperative specimens were detected pathological examination.The difference and consistence rates of the results of TCT,colposcopic multiple biopsies and LEEP were compared.Result:The coincidence rate of TCT and colposcopy biopsy results was LSIL 81.25%,HSIL 89.66%,respectively.The overall consistence rate of pathology between colposcopic multiple biopsies and post-LEEP was 70.75%,and those of CIN-Ⅰ,CIN-Ⅱ and CIN-Ⅲ were 59.18%,79.31%,82.14%,respectively(P0.05).Conclusion:TCT and the colposcopic directed biopsy are the major monitoring way in cervical cancer and high-grade CIN.LEEP is an effective method of diagnosis and treatment of CIN and it could reduce the rate of misdiagnosis and missed diagnosis.