The therapeutic effect of Seretide inhalation with different type on moderate bronchial asthma

Objective To observe the clinical effect of Seretide inhalation on patients with moderate bronchial asthma,and to compare different dose of seretide inhalation(50/500 and 50/250).Methods One hundred patients with moderate bronchia asthma were randomly divided into two groups treated with Seretide 50/250 and Seretide 50/500 lasted for 12 weeks.The pulmonary function(PEF,PEF%,FEV,FEV1%)and clinical symptom were monitored in two groups before and after the treatment.Results The clinical symptoms were obviously improved in both two groups.The totally effective rate was 96.0% in treatment group,and higher than control group(86.0%)(P0.05).The forced expiratory volume in 1 second(FEV_1)and the FEV_1% after treatment improved significantly in both two groups(P0.05).In the meantime,the PEF and the PEF% in the predicted value(PEF%)were improved in two groups(P0.05),while there has still significant difference between the two groups,the remission rate in the group of Seretide 50/500 was significantly higher than that in the group of Seretide 50/250(P0.05).The time of asthma partly controlled and totally controlled in Seretide 50/250 group(24.7 d±1.3 d,46.7 d±1.5 d)was longer than that in the group of Seretide 50/250(16.9 d±1.7 d,38.8 d±1.8 d).Conclusion The symptoms could be improvement shortly after inhalation Seretide in moderate bronchia asthma.In the beginning state,the dosage of 50/500 had better effect than dosage of 50/250.