Study Clinical Investigation the Relationship between Coronary Angiographic Findings and the Left Ventricular Function

Objective In this study we try to determine the relationship between coronary angiographic findings and the left ventricular function. Methods We evaluated 243 patients undergoing coronary angiography and echocardiology, so as to investigate the coronary pathological changes and their influence on left ventricular structure and function. Results With the coronary pathological changes becoming more serious, end diastolic diameter of left ventricle(Dd),left ventricular mass(LVmass), end diastolic volume of left ventricle(EDV) and end systolic diameter of left ventricle(ESV) increased significantly,meanwhile,ejection fraction(EF) and fractional shortening of the minor semi axis(FS) significantly decreased,but the ratio of atrial peak flow velocity (APFV) to early peak flow velocity (EPFV) was significantly higher. Conclusion The left ventricular structure and diastolic function of those patients with coronary artery disease had significantly changed in their early stage.As coronary artery encroached by the obstruction (with critical narrowing above 50%), the left ventricular systolic disfunction would be found,The difference were significant between the normal and those patients with critical narrowing above 50%,nevertheless,there were no significant difference between the coronary single vessel disease to three vessel disease. The study suggested that the ratio of APFV to EPFV was the criteria for diagnosis in left ventricular diastolic function.Those patients with critical narrowing below 50% should be paid more attention. [