APPLICATION OF MRI IN PREOPERATIVE DIAGNOSIS AND STAGING IN RECTAL CANCER
Guo Chen
Abstract
Guo Chen
Abstract
Objective To assess the value of magnetic resonance imaging(MRI) in preoperative diagnosis and clinical staging of rectal cancer. Methods A TN staging was undertaken by MRI in 48 patients with rectal cancer,the result was compared with pathology. Results The final diagnosis for rectal cancer by MRI was 100%.For T staging,39 cases were correct,and nine were wrong: in which,six cases with T1-T2 were reported as T3;three with T3 reported as T1-T2.The totally accurate rate of T staging was 81.3%(39/48),in which,the accuracy in T1-T2 staging was 86.3%(19/22),in T3 was 66.7%(12/18) and T4 was 100%(8/8).A statistic analysis indicated that preoperative MRI staging was better consistent with pathologic staging(Kappa=0.696,P0.01).For MRI lymph node staging,the accurate was 36 cases,error in 12;in which,overstaged and understaged was six,respectively.The accuracy of node staging was 75.0%(36/48),sensitivity was 68.4%(13/19),and specificity was 79.3%(23/29).MRI could make a relatively correct prediction for lymph node staging in cancer of the rectum(Kappa=0.573,P0.05). Conclusion Preoperative MRI staging can relatively make an exact evaluation of the depth of tumor infiltration and lymph node metastasis and TN staging in rectal cancer.
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Objective To assess the value of magnetic resonance imaging(MRI) in preoperative diagnosis and clinical staging of rectal cancer. Methods A TN staging was undertaken by MRI in 48 patients with rectal cancer,the result was compared with pathology. Results The final diagnosis for rectal cancer by MRI was 100%.For T staging,39 cases were correct,and nine were wrong: in which,six cases with T1-T2 were reported as T3;three with T3 reported as T1-T2.The totally accurate rate of T staging was 81.3%(39/48),in which,the accuracy in T1-T2 staging was 86.3%(19/22),in T3 was 66.7%(12/18) and T4 was 100%(8/8).A statistic analysis indicated that preoperative MRI staging was better consistent with pathologic staging(Kappa=0.696,P0.01).For MRI lymph node staging,the accurate was 36 cases,error in 12;in which,overstaged and understaged was six,respectively.The accuracy of node staging was 75.0%(36/48),sensitivity was 68.4%(13/19),and specificity was 79.3%(23/29).MRI could make a relatively correct prediction for lymph node staging in cancer of the rectum(Kappa=0.573,P0.05). Conclusion Preoperative MRI staging can relatively make an exact evaluation of the depth of tumor infiltration and lymph node metastasis and TN staging in rectal cancer.
Key concepts: Medicine, Colorectal cancer, Magnetic resonance imaging, Lymph node, Rectum, Radiology, Tumor Staging, Cancer staging