Effect of low-dose ropivacaine-sufentanil in spinal anesthesia for cesarean delivery

Objective:To explore the effect of low-dose ropivacaine combined with sufentanil in spinal anesthesia for cesarean section and evaluate its sensory-motor block effects and adverse reactions,in comparison with use of bupivacaine and ropivacaine,respectively. Methods:Sixty six cases of elective cesarean section under spinal or combined spinal-epidural anesthesia were divided into three groups:Group B (bupivacaine 8 mg),Group R (ropivacaine 12 mg),Group RS (Ropivacaine 9 mg+Sufentanil 5 μg). Indexes of sensory nerve block and motor nerve block and intraoperative adverse events were observed and recorded. Results:Hemodynamic indexes of Group B was most volatile while that of group RS was most stable,which was significantly different from group B (P0.05). Sensory nerve block of Group RS was the best,group B followed,and group R was the worst. The motor nerve block was obviously completed and prolonged in Group B than the other two groups (P0.05). The motor nerve block degree of RS Group was similar with Group R,but with faster recovery (P0.05). Group RS's sedation score were higher than the other two groups (P0.05). Adverse events incidence of Group RS,such as nausea,vomiting,shiver and traction pain,were significant lower than the other two group(P0.05),while the itching incidence was higher than Group B and R(P0.05). Conclusion:Combined use of ropivacaine (9 mg) and sufentanil (5 μg) in spinal anesthesia had perfect analgesic and muscle relaxant effect for cesarean section patients,with stable hemodynamics,quick postoperative muscle relaxant and fewer adverse reactions.