2014•Hainan yixueRequires access

Spinal anesthesia with ropivacaine combined with sufentanil in the elder patients

Zhang Cai-lin

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Abstract

Objective To discuss the clinical effectivity and safety of spinal anesthesia with ropivacaine combined with sufentanil in the elderly.Methods Spinal anesthesia was performed in 150 patients,aged more than 85 years old and undergoing selective lower limb surgery,who were equally randomized into three groups.A group received 0.5% ropivacaine 7.5 mg plus sufentanil 1.5 μg.B group received 0.5% ropivacaine 7.5 mg plus sufentanil 2.5 μ g.C group received 0.5% ropivacaine 7.5 mg plus sufentanil 3.5 μ g.Compare the situation of sensorimotor block,hemodynamic changes,and side effects in three groups after spinal anesthesia.Results The MAP,HR of three group after spinal anesthesia had no significant difference among them.In terms of sensorimotor block effect,B group and C group were better than group A(P0.05),but there was no statistical significance between B group and C group.At the comparisons of side effects after spinal anesthesia,only the incidence of urinary retention in group C was significantly higher than that in group A and group B(P0.05),the incidence of the side effects were not increasing significantly.Conclusion Small dose of ropivacaine combined with sufentanil can be effectively and safely applied to elderly patients with operation.The scheme of 0.5% ropivacaine 7.5 mg plus sufentanil 2.5 μg among them has the best effect and the minimum side effects.

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Objective To discuss the clinical effectivity and safety of spinal anesthesia with ropivacaine combined with sufentanil in the elderly.Methods Spinal anesthesia was performed in 150 patients,aged more than 85 years old and undergoing selective lower limb surgery,who were equally randomized into three groups.A group received 0.5% ropivacaine 7.5 mg plus sufentanil 1.5 μg.B group received 0.5% ropivacaine 7.5 mg plus sufentanil 2.5 μ g.C group received 0.5% ropivacaine 7.5 mg plus sufentanil 3.5 μ g.Compare the situation of sensorimotor block,hemodynamic changes,and side effects in three groups after spinal anesthesia.Results The MAP,HR of three group after spinal anesthesia had no significant difference among them.In terms of sensorimotor block effect,B group and C group were better than group A(P0.05),but there was no statistical significance between B group and C group.At the comparisons of side effects after spinal anesthesia,only the incidence of urinary retention in group C was significantly higher than that in group A and group B(P0.05),the incidence of the side effects were not increasing significantly.Conclusion Small dose of ropivacaine combined with sufentanil can be effectively and safely applied to elderly patients with operation.The scheme of 0.5% ropivacaine 7.5 mg plus sufentanil 2.5 μg among them has the best effect and the minimum side effects.

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Objective To discuss the clinical effectivity and safety of spinal anesthesia with ropivacaine combined with sufentanil in the elderly.Methods Spinal anesthesia was performed in 150 patients,aged more than 85 years old and undergoing selective lower limb surgery,who were equally randomized into three groups.A group received 0.5% ropivacaine 7.5 mg plus sufentanil 1.5 μg.B group received 0.5% ropivacaine 7.5 mg plus sufentanil 2.5 μ g.C group received 0.5% ropivacaine 7.5 mg plus sufentanil 3.5 μ g.Compare the situation of sensorimotor block,hemodynamic changes,and side effects in three groups after spinal anesthesia.Results The MAP,HR of three group after spinal anesthesia had no significant difference among them.In terms of sensorimotor block effect,B group and C group were better than group A(P0.05),but there was no statistical significance between B group and C group.At the comparisons of side effects after spinal anesthesia,only the incidence of urinary retention in group C was significantly higher than that in group A and group B(P0.05),the incidence of the side effects were not increasing significantly.Conclusion Small dose of ropivacaine combined with sufentanil can be effectively and safely applied to elderly patients with operation.The scheme of 0.5% ropivacaine 7.5 mg plus sufentanil 2.5 μg among them has the best effect and the minimum side effects.

Key concepts: Ropivacaine, Sufentanil, Medicine, Anesthesia, Group B, Spinal anesthesia, Incidence (geometry), Hemodynamics

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