Clinical Observation on Ziyin Qinggan Xiaocuo Prescription Combined with Cuo Ling Tincture for Adult Female Acne Vulgaris with Yin Deficiency and Liver Heat

【Objective】To investigate the method of nourishing yin and clearing liver for adult female acne vulgaris(AV) with Yin deficiency and liver heat.【Methods】One hundred and twenty adult female AV patients were randomized into two groups by random number table.The two groups received external application of Cuo Ling Tincture(CLT,mainly composed of Radix Salviae Miltiorrhizae,Radix Angelicae Dahuricae,Radix Astragali,etc.),and group A was treated with Ziyin Qinggan Xiaocuo Prescription(ZQXP,mainly composed of Fructus Ligustri Lucidi,Herba Ecliptae,Radix Bupleuri,Radix Salviae Miltiorrhizae,etc.)and group B with minocyclin additionally.The treatment lasted 28 days.After treatment,the therapeutic effect were compared between the two groups.【Results】In group A,4 were cured,14 markedly effective,26 effective and 8 ineffective,the total effective rate being 84.6%.In group B,5 were cured,13 markedly effective,25 effective and 5 ineffective,the total effective rate being 89.6%,which is similar to that in group A(P0.05).Adverse action was found in 7 patients of group A and in 9 of group B.【Conclusion】ZQXP has a good therapeutic effect for adult female AV,which is similar to minocyclin.Meanwhile,ZQXP has less and slight adverse actions.