Effects of Shenlingbaizhu Powder and Mesalazine on the IL-17, IL-23 and TNF-α of Patients with Ulcerative Colitis

Objective: To explore the effects of Shenlingbaishu powder combined with salad oxazine on the treatment of ulcerative colitis and its influence on levels of cytokines. Methods: The patients with ulcerative colitis who were treated in our hospital from January 2013 to 2014 were selected and randomly divided into the observation group and the control group. The patients in the observation group were treated by shenlingbaizhu powder combined with mesalazine, while the patients in the control group were treated with the salad oxazine. Then the levels of cytokines in serum of patients were detected and compared between the two groups. Results:The total effective rate of observation group was better than that of the control group with statistically significant difference(P0.05);After the treatment, the Sutherland DAI score of patients in the two groups improved, and the observation group was better than that of the control group with statistically significant difference(P0.01); The expression levels of IL-17, IL-23 and TNF-a reducedand the observation group was lower than those of the control group with statistically significant differences(P0.01). Conclusion: The effect of Shenlingbaizhu powder combined with mesalazine on the treatment of ulcerative colitis could be better with the improvement of the cytokines levels.