Report of 50 Cases of Non-invasive Ventilation Treatment of Chronic Obstructive Pulmonary Disease in Acute Exacerbation

Objective To report the blood gas results and improved dyspnea symptoms of non-invasive ventilation in patients with chronic obstructive pulmonary disease in acute exacerbation(AECOPD).Methods 50 cases of AECOPD patients from January to June2013 were selected as the control group,and they were given with conventional treatment,including antibiotics,corticosteroids,expectorant asthma medication class,and low-flow oxygen via nasal cannula therapy; 50 cases of AECOPD patients from July to December 2013 were selected as the study group,and they received non-invasive ventilation therapy in addition.Results The difference of PaO2and PaCO2of the two groups before treatment was not statistically significant(P 0.05).But they were significantly improved after treatment.PaO2of the study group after treatment was significantly higher than that of the control group.PaCO2was significantly lower than that of the control group.The difference between the two groups was statistically significant(P 0.01).40.0%,64.0%,72.0% and 96.0% of the study group had better dyspnea symptoms in 12,24,48 and 72 h after treatment,significantly better than those of the control group(16.0%,28.0%,48.0% and 56.0%,respectively)(P 0.05).Conclusions The treatment of non-invasive ventilation which is easier to receive for patients with AECOPD can improve arterial blood gas index,and relieve dyspnea.