2009Journal of Anhui Traditional Chinese Medical CollegeRequires access

Preparation Process of Paeonol-β-cyclodextrin Inclusion Compound

Fan Qing-guo

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Abstract

Objective:To optimize the preparation process for Paeonol-β-cyclodextrin Inclusion Compound.Methods:An orthogonal design was employed.The yields of inclusion compound and inclusion rate were used as evaluation index.The inclusion process was chosen based on optimizing the inclusion time,inclusion temperature and the ratio of β-cyclodextrin to paeonol.Results:The optimum inclusion conditions were as follows: the inclusion time was 4.5 h,the inclusion temperature was 60 ℃,and the ratio of β-cyclodextrin to paeonol was 1∶10(g∶g).Conclusion:The optimized inclusion process is feasible.

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Objective:To optimize the preparation process for Paeonol-β-cyclodextrin Inclusion Compound.Methods:An orthogonal design was employed.The yields of inclusion compound and inclusion rate were used as evaluation index.The inclusion process was chosen based on optimizing the inclusion time,inclusion temperature and the ratio of β-cyclodextrin to paeonol.Results:The optimum inclusion conditions were as follows: the inclusion time was 4.5 h,the inclusion temperature was 60 ℃,and the ratio of β-cyclodextrin to paeonol was 1∶10(g∶g).Conclusion:The optimized inclusion process is feasible.

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Available abstract

Objective:To optimize the preparation process for Paeonol-β-cyclodextrin Inclusion Compound.Methods:An orthogonal design was employed.The yields of inclusion compound and inclusion rate were used as evaluation index.The inclusion process was chosen based on optimizing the inclusion time,inclusion temperature and the ratio of β-cyclodextrin to paeonol.Results:The optimum inclusion conditions were as follows: the inclusion time was 4.5 h,the inclusion temperature was 60 ℃,and the ratio of β-cyclodextrin to paeonol was 1∶10(g∶g).Conclusion:The optimized inclusion process is feasible.

Key concepts: Paeonol, Cyclodextrin, Inclusion (mineral), Inclusion compound, Chemistry, Process (computing), Chromatography, Computer science

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