ANALYSIS OF PRENATAL SCREENING SITUATION IN SICHUAN AREA FROM 2007 TO 2009

[Objective]To analyses the prenatal screening situation in Sichuan area.[Methods]The concentrations of AFP,free βhCG and μE3 in the serum of mid-trimester(15-20 weeks pregnancy)pregnant women were tested.The risk of Down syndrome,Trisomy 18 and Nervous tube defect were evaluated by using the risk evaluation software.[Results]In the three years,the total rate of prenatal screening was 5.08%.Among the high risk and low risk pregnant women,the total positive rate was 23.68% and 8.59%,respectively.In the high risk group,the positive rate of Down syndrome,Trisomy 18 and Nervous tube defect were 21.46%,0.96% and 1.26%,respectively;In the low risk group,they were 7.34%,0.13% and 1.11%,respectively.[Conclusion]As the second level intervention measure of birth defect,prenatal screening played an important role in decreasing birth defect rate,but it should be further popularized.