2010•Chronic Pathematology JournalRequires access

The Relation between Serum HBV DNA and the Grades of Liver Inflammation in Chronic Hepatitis B Virus Carriers

X Chen

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Abstract

Objective To study the relationship between the qualification of HBV DNA and the liver inflammation in chronic hepatitis B virus (HBV)arriers.Methods 244 chronic HBV carriers were examined with Liver biopsy、liver function、HBV-DNA level and serological markers of B-hepatitis.examination.Groups were divided based on the grades of liver inflammation and serum HBV DNA levels.Results All of the 244 cases,48(19.7%)had inflammation stage G≥ 2,No significant differences were observed in the inflammation between HBV DNA high/low groups.Conclusion Most chronic HBV carriers had mild inflammatory histological changes in their livers.the grades of liver inflammation were not correlated with HBV DNA in sera.

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Objective To study the relationship between the qualification of HBV DNA and the liver inflammation in chronic hepatitis B virus (HBV)arriers.Methods 244 chronic HBV carriers were examined with Liver biopsy、liver function、HBV-DNA level and serological markers of B-hepatitis.examination.Groups were divided based on the grades of liver inflammation and serum HBV DNA levels.Results All of the 244 cases,48(19.7%)had inflammation stage G≥ 2,No significant differences were observed in the inflammation between HBV DNA high/low groups.Conclusion Most chronic HBV carriers had mild inflammatory histological changes in their livers.the grades of liver inflammation were not correlated with HBV DNA in sera.

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Available abstract

Objective To study the relationship between the qualification of HBV DNA and the liver inflammation in chronic hepatitis B virus (HBV)arriers.Methods 244 chronic HBV carriers were examined with Liver biopsy、liver function、HBV-DNA level and serological markers of B-hepatitis.examination.Groups were divided based on the grades of liver inflammation and serum HBV DNA levels.Results All of the 244 cases,48(19.7%)had inflammation stage G≥ 2,No significant differences were observed in the inflammation between HBV DNA high/low groups.Conclusion Most chronic HBV carriers had mild inflammatory histological changes in their livers.the grades of liver inflammation were not correlated with HBV DNA in sera.

Key concepts: Medicine, Inflammation, Hepatitis B virus, Liver biopsy, Immunology, Hepatitis B, Liver function, Serology

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