2012•Journal of Practical Traditional Chinese Internal MedicineRequires access

Fuzheng Xiezhuo Decoction's Curative Effects to Adenine-Induced Chronic Renal Failure Rats Experiment then Aparallel Control Study Research

Shengzhi Wang

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Abstract

[Objective]To observe Fuzheng Xiezhuo decoction's curative effects on the levels of BUN,Scr,Hb,MCP-1 and TGF-β1 of adenine-induced chronic renal failure rats.[Method]rats were randomly divided into normal group,control group,model group,high-dose group and low-dose group.Then the curative effects were observed and compared.[Results]Fuzheng Xiezhuo decoction's effects were obviously better than control group's(P0.05).[Conclusion]Fuzheng Xiezhuo decoction has obvious curative effects on improving the renal function of adenine-induced chronic renal failure and can reduce the production of factors leading to fibrosis.

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What this paper is about

[Objective]To observe Fuzheng Xiezhuo decoction's curative effects on the levels of BUN,Scr,Hb,MCP-1 and TGF-β1 of adenine-induced chronic renal failure rats.[Method]rats were randomly divided into normal group,control group,model group,high-dose group and low-dose group.Then the curative effects were observed and compared.[Results]Fuzheng Xiezhuo decoction's effects were obviously better than control group's(P0.05).[Conclusion]Fuzheng Xiezhuo decoction has obvious curative effects on improving the renal function of adenine-induced chronic renal failure and can reduce the production of factors leading to fibrosis.

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Available abstract

[Objective]To observe Fuzheng Xiezhuo decoction's curative effects on the levels of BUN,Scr,Hb,MCP-1 and TGF-β1 of adenine-induced chronic renal failure rats.[Method]rats were randomly divided into normal group,control group,model group,high-dose group and low-dose group.Then the curative effects were observed and compared.[Results]Fuzheng Xiezhuo decoction's effects were obviously better than control group's(P0.05).[Conclusion]Fuzheng Xiezhuo decoction has obvious curative effects on improving the renal function of adenine-induced chronic renal failure and can reduce the production of factors leading to fibrosis.

Key concepts: Medicine, Decoction, Chronic renal failure, Internal medicine, Gastroenterology, Renal function

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