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Study on Pathogenesis of Slow Transit Constipation

Yihong Fan

Open publisher page 1 citations

Abstract

The pathogenesis of slow transit constipation(STC) is mainly correlated with enteric nervous system(ENS),interstitial cells of Cajal(ICC),smooth muscle and neurotransmitters.Studies have shown that degenerative changes of ENS,vacuolar degeneration of myenteric nerve plexus,decreased number of ICC,morphological changes,degenerative changes of smooth muscle and changes of neurotransmitters are seen in STC colonic tissue.This article reviewed the study on pathogenesis of STC.

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What this paper is about

The pathogenesis of slow transit constipation(STC) is mainly correlated with enteric nervous system(ENS),interstitial cells of Cajal(ICC),smooth muscle and neurotransmitters.Studies have shown that degenerative changes of ENS,vacuolar degeneration of myenteric nerve plexus,decreased number of ICC,morphological changes,degenerative changes of smooth muscle and changes of neurotransmitters are seen in STC colonic tissue.This article reviewed the study on pathogenesis of STC.

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Available abstract

The pathogenesis of slow transit constipation(STC) is mainly correlated with enteric nervous system(ENS),interstitial cells of Cajal(ICC),smooth muscle and neurotransmitters.Studies have shown that degenerative changes of ENS,vacuolar degeneration of myenteric nerve plexus,decreased number of ICC,morphological changes,degenerative changes of smooth muscle and changes of neurotransmitters are seen in STC colonic tissue.This article reviewed the study on pathogenesis of STC.

Key concepts: Pathogenesis, Interstitial cell of Cajal, Myenteric plexus, Enteric nervous system, Constipation, Pathology, Medicine, Plexus

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