Analysis of infection types of human papillomavirus in women of Changzhou district

Objective To understand HPV prevalence and HPV genotypes distribution of cervical cancer though the inspection of HPV subtypes,and to study the infection genotypes of human papillomavirus in women of Changzhou district.Methods We exfoliated cells prepared from cervical biopsy and detected the infection genotypes of human papillomavirus by using flow-through hybridization and gene chip(HybriMax) technology.Results Among 2 061 women samples,535 specimens were tested positive for HPV infection and HPV infection rate was 25.95%,the top five picks were HPV16,58,52,33,31.119 cases were infected with two HPV genotypes and the infection rate was 22.24%.27 cases were infected with three HPV genotypes and the infection rate was 5.05%.8 cases were infected with four HPV genotypes and the infection rate was 1.05%.1 case was infected with five HPV genotypes and the infection rate was 0.19%.Conclusion The infection rate of HPV in local women is 25.95%,the main infection are HPV16,58,and secondly are 52,33,31,and the genotype of mixed infection cases mainly is the high risk infection.