Analysis of Pregnant Outcome and Fasting Blood Glucose of Pregnant Women with Gestationl Diabetes Mellitus

【Objective】 To study the feature of the fasting blood glucose and its effect on the pregnant outcome of the women with gestation diabetes mellitus (GDM). 【Methods】 Retrospective analysis was utilized to analyze the FBG and the pregnant outcome of 182 in-and out-pregnant women who were diagnosed as GDM in the 3th Affiliated Hospital of SUN Yet Sen University from January 2006 to June 2007. According to the FBG results of 75g oral glucose tolerance test (OGTT) or FBG, the patients were divided into Group A with the normal FBG and Group B with the elevating FBG . 【Result】 FBG was positively related with the plasma glucose of every time point in the glucose challenge test (GCT) and the OGTT. The women with FBS ≥ 5.8 mmol / L took up 71.1% of the women with the plasma glucose of GCT1h equal or more than 11.1 mmol / L. There were no significant difference between the two groups in the pregnancy complication. The rate of insulin treatment in Group B (19.1%) is much higher than Group A (5.3%) (P 0.05). The birth weight in Group B as well as the rate of fetal macrosomia, the neonatal asphyxia and the newborn hyperbilirubinemia was higher than that in group A. 【Conclusion】 FBS must be examined for the diagnosis of GDM if the plasma glucose of GCT1h is equal or more than 11.1 mmol / L. The risk of the perinatal fetus in the patients of GDM rises with the elevation of FBG, which need the strengthening monitoring.