Chemical constituents from Ainsliaea glabra
Chen Ya
Abstract
Chen Ya
Abstract
To investigate the chemical constituents of Ainsliaea glabra,several chromatographies including Silica gel column chromatography and Sephadex LH-20gel column chromatography were applied to the isolation and purification of chemical constituents.The structures were identified on the basis of chemical evidence and spectral data.The results showed that seventeen compounds were isolated fromA.glabraand they were identified as taraxasteryl acetate(1),dotriacont-1-ene(2),β-sitosterol(3),chrysophanol(4),lupenyl palmitate(5),methyl linolenate(6),linoleic acid(7),phytol(8),stigmast-4-en-3-one(9),phytenal(10),betulinic acid(11),(9Z,11E)-13-oxo-9,11-ocatadecadienoic acid(12),E-7,9-diene-11-methenyl palmitic acid(13),taraxinic acid(14),3β-hydroxy-cholesta-5-ene(15),epoxylycopaene(16),28-O-laurylbetulin(17).Compounds 1-17 were obtained from this herb for the first time.
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To investigate the chemical constituents of Ainsliaea glabra,several chromatographies including Silica gel column chromatography and Sephadex LH-20gel column chromatography were applied to the isolation and purification of chemical constituents.The structures were identified on the basis of chemical evidence and spectral data.The results showed that seventeen compounds were isolated fromA.glabraand they were identified as taraxasteryl acetate(1),dotriacont-1-ene(2),β-sitosterol(3),chrysophanol(4),lupenyl palmitate(5),methyl linolenate(6),linoleic acid(7),phytol(8),stigmast-4-en-3-one(9),phytenal(10),betulinic acid(11),(9Z,11E)-13-oxo-9,11-ocatadecadienoic acid(12),E-7,9-diene-11-methenyl palmitic acid(13),taraxinic acid(14),3β-hydroxy-cholesta-5-ene(15),epoxylycopaene(16),28-O-laurylbetulin(17).Compounds 1-17 were obtained from this herb for the first time.
Key concepts: Palmitic acid, Phytol, Column chromatography, Chemistry, Chemical constituents, Chromatography, Silica gel, Sephadex