Clinical Study of 725 Cases on Combined Inhaled Seretide and Tiotropium Bromide in the Treatment of Chronic Obstructive Pulmonary Disease

Objective To study the combined inhaled seretide and tiotropium bromide in the treatment of chronic obstructive pulmonary disease(COPD)during the stable period of efficacy and safety.Methods 725 patients with COPD,were randomly divided into the observation group 364 cases,361 cases of the control group.The control group was given tiotropium bromide 18μg,daily bedtime inhaled 1 times,60 days for a course of treatment;added to the observation group in 50g/500g,sooner or later the inhalation of 1,course of treatment and control group.In two groups before and after treatment,symptom score and pulmonary function examination.Results The two groups of patients after treatment of symptom scores have improved,the curative effect of therapeutic group was more significant at P0.05.Two groups of patients after treatment of pulmonary function were all improved,the curative effect of therapeutic group was more significant at P0.05.Safety indexes before and after treatment had no significant difference between P 0.05.Conclusion The combined inhalation of tiotropium bromide + Seretide can effectively reduce COPD patients with clinical symptoms,improve lung function,safe and reliable,worthy of clinical application.