Study of Different Enteral Nutrition on Bacterial Translocation and Intestinal Morphology during the Intraoperative Period

Objective: To examine the effects of various enteral nutrients on bacterial translocation and intestinal morphology in the colon cancer patients during the intraoperative period.Methods: 160 patients were randomly divided into four groups.All patients had radical operation and got bowel preparation three days before operation.Group I were provided with intravenous nutrition;group II was given Elemental Powders;group III,general enteral nutrients;group IV,Ensure.Bacterial translocation was detected by endotoxin and diamine oxidase.Changes in the colon were scored from 0 to 5 with the morphologic scoring system.Results: Patients given ensure(group IV) showed a significant reduction in bacterial translocation as compared with other groups.The endotoxin levels were decreased in all groups after treatment,and it was lower in groups II-IV at d1,d4,d7 after treatment than in group I,especially was the lowest in group IV(P0.05).The histologic scores of group IV were statistically different from the other three groups,and the score of group I-IV is respectively 2.35±0.72,1.92±1.07,1.75±1.03 and 0.92±0.95.Conclusion: Enteral diets supplemented with Ensure were found to reduce bacterial translocation and protect intestinal mucosa.