Acute toxicity and toxicity of acetylcholinesterase of Chinese ocellated gudgeon exposed to triazophos
Xiquan Shen
Abstract
Xiquan Shen
Abstract
This research presents the Chinese ocellated gudgeon that exposed to triazophos for different time and pesticide concentrations.The results of acute toxicity and acetylcholinesterase(AChE) toxicity were gained:(1) 50% lethal concentrations(LC50) of experimental fish were 635,241,116 and 58 μg/L for 12,24,36 and 48 h exposure time respectively.(2) Chinese ocellated gudgeon were exposed to triazophos for 24 h,the brain AChE activity of fish were significantly different among different concentration groups(P0.05).After 48h exposure time,the AChE activity of low concentration groups(1~100 μg/L) showed the significant differences,but that in the high concentration groups(500~1 000 μg/L) were not significant differences(P0.05).(3)With the exposure concentration and enhancing time,the AChE activity inhibition was corresponding increased.Under the low concentration conditions exposed(1~10 μg/L),the inhibition of AChE activity were well gradient as the exposure concentration increased.Among high concentration exposure groups,the inhibition of AChE showed not significant differences with the exposure concentration and time rising.
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This research presents the Chinese ocellated gudgeon that exposed to triazophos for different time and pesticide concentrations.The results of acute toxicity and acetylcholinesterase(AChE) toxicity were gained:(1) 50% lethal concentrations(LC50) of experimental fish were 635,241,116 and 58 μg/L for 12,24,36 and 48 h exposure time respectively.(2) Chinese ocellated gudgeon were exposed to triazophos for 24 h,the brain AChE activity of fish were significantly different among different concentration groups(P0.05).After 48h exposure time,the AChE activity of low concentration groups(1~100 μg/L) showed the significant differences,but that in the high concentration groups(500~1 000 μg/L) were not significant differences(P0.05).(3)With the exposure concentration and enhancing time,the AChE activity inhibition was corresponding increased.Under the low concentration conditions exposed(1~10 μg/L),the inhibition of AChE activity were well gradient as the exposure concentration increased.Among high concentration exposure groups,the inhibition of AChE showed not significant differences with the exposure concentration and time rising.
Key concepts: Aché, Acetylcholinesterase, Toxicity, Toxicology, Fish <Actinopterygii>, Acute toxicity, Biology, Pharmacology