Preparation of Highly Deacetylated Chitosan by Phase Transfer Catalyst

The chitosan was prepared with 92% deacetylation degree using n-butanol and sodium hydroxide as a reaction medium and cetyltrimethylammonium bromide as a phase transfer catalyst. The optimal reaction conditions were established as follows: chitin was 1.5 g, w(catalyst ) was 7%(mass ratio of chitin), reaction temperature was 120 ℃, reaction time was 2 h, m(chitin) ∶ m(sodium hydroxide) ∶m(n-butanol) =1 ∶3 ∶16.