Clinic value of bone marrow histopathology in diagnosis and differential diagnosis of hematonosis

Objective To study the diagnostic significance of synchronism observation on both marrow biopsy and marrow smear in hematological diseases.Methods The marrow samples of 650 patients with hematological diseases were detected by peripheral blood smear,bone marrow biopsy and bone marrow smear.Those sections and smears were observed.Results Bone marrow biopsy showed the hyperplasia of bone cells more accurately and had a higher checkout rate of the malignant cells.Biopsy prefered to smear in the diagnosis of diseases such as lymphoma,myelofibrosis,myelodysplastic syndrome,metastatic carcinoma of bone marrow and multiple myeloma.Conclusion Bone marrow biopsy and bone marrow smear synchronous observation can effectively increase the diagnosis rate,decrease misdiagnosis rate, and judge correctly the stage of the disease.