Clinical analysis of 65 patients with intraductal papillomas

Objective To investigate the characteristics,diagnosis and treatment of the intraductal papillomatosis.Methods The clinical data of 65 patients who had been pathologically diagnosed as having intraductal papilloma or intraductal papillomatesis from November 2000 to September 2011 were analyzed retrospectively.Results Among the 65 patients,49(75.4%) had nipple discharge,including light bloody discharge in 32 patients(65.3%) and yellow discharge in 17(34.7%).Sixteen patients(24.6%) were diagnosed with masses of the nipple and areola area.Intraductal papilloma was found pathologically in 56 patients,intraductal papillomatosis in 5,and papillomatosis with malignant transformation in 4.Forty-nine patients with nipple discharge were detected by breast Duct endoscopy,with a detection rate was 85.7%.Conclusions Nipple dischange is the most common symptom in patients with intraductal papilloma.Breast Duct endoscopy is a valuable method for the diagnosis of intraductal papillomas.Carcinoma change may be possible in intraductal papillomatosis.