Reserach of learing curve of sentinel lymph node biopsy in breast cancer

Objective To evaluate the learning curve and the efficacy of sentinel lymph node biopsy(SLNB)by the breast surgeon in the existing medical conditions.Methods Forty cases of breast tumor without axillary lymph node(ALN)by palpation were enrolled in this study.And using the methylene blue as the tracer agent,All patients were treated by segment resection plus axillary lymph node dissection(ALND).Biopsies of sentinel lymph nodes and axillary lymph nodes were taken in all patients.Results The SLN were detected in 38 patients,11 cases has metasis and 27 cases has no metasis,the accurate rate of SLNB was 95%,1 case was negative detected by the rapid pathology but positive by the routine pathology,its false negative rate was 9.09%(1/11).There was no significant difference between the effect of detection of metastasis by sentinel lymph node or axillary lymph node biopsy.Conclusion The SLN of the breast cancer can accurately reflect the status of the patients with armpit lymph node,SLNB replacing ALND will be a standard handler for the early stage breast cancer without ALN by palpation.