Taking Antihypertensive Drugs in Consistency with the Circadian Rhythm of Blood Pressure

This Article retrieved literatures about the relationship between the time of administration antihypertensive drugs and the circadian rhythm of blood pressure,evaluated the effect of administration antihypertensive at bedtime,provided recommendation of how to take antihypertensive.Firstly,most patient should to take antihypertensive in the morning.Secondly,about 20 percent of patient show abnormal circadian rhythm of blood pressure,that is mean non-dipper hypertension through ambulatory blood pressure monitoring,should adjust the medication administration from morning to night or morning and night.Thirdly,antihypertensive which are chosen to administrate at bedtime should be long time acting.Administration hypertensive at bedtime will help restore the normal circadian rhythm of blood pressure,alleviate the morning surge,and reduce even reverse the damage to target organs.