Determination of fifty pesticide residues in vegetables by using solid phase extraction-gas chromatography/tandem mass spectrometry

A method was developed for determination of 50 pesticide residues in vegetables by using gas chromatography-tandem mass spectrometry(GC/MS/MS).The samples were extracted with acetonitrile and cleaned up by solid phase extraction.The extracts were determined by GC/MS/MS using external standard method.The linearity of the method was good between 10 μg/L and 500 μg/L.The method was reliable and stable that the recoveries of 50 pesticides were in the range from 77.30% to 116.91% and the relative standard deviations were all not more than 15%.The limits of detection and the limits of quantitation were 0.1~5.0 μg/kg and 0.3~16.7 μg/kg respectively.The method was simple,accurate and sensitive,and was suitable for the simultaneous analysis of various pesticides residues in vegetables.It can satisfy the legislations on monitoring of pesticide residues in vegetables required by the European Union,Japan and other countries.