2010Anhui Medical and Pharmaceutical JournalRequires access

Effect of L-ornithine-L-aspartate combined with lactulose in the treatment of patients with hepatic encephalopathy after hepatic cirrhosis

Xiaowu Hu

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Abstract

Aim To explore the effect of L-ornithine-L-aspartate combined with lactulose in the treatment of patients with hepatic encephalopathy after hepatic cirrhosis.Methods 68 patients with hepatic encephalopathy were selected and 17 patients received treatment of aceglutamide,28 patients received treatment of L-ornithine-L-aspartate and other 23 L-ornithine-L-aspartate combined with lactulose.Result The mortality rate,similar to that in L-ornithine-L-aspartate therapy(25%),in L-ornithine-L-aspartate combined with lactulose treatment was 21.7%,much lower than that in aceglutamide treatment group(47.1%,P0.05).Conclusion L-ornithine-L-aspartate combined with lactulose in the treatment of patients with hepatic encephalopathy can effectively decrease the mortality rate.

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Aim To explore the effect of L-ornithine-L-aspartate combined with lactulose in the treatment of patients with hepatic encephalopathy after hepatic cirrhosis.Methods 68 patients with hepatic encephalopathy were selected and 17 patients received treatment of aceglutamide,28 patients received treatment of L-ornithine-L-aspartate and other 23 L-ornithine-L-aspartate combined with lactulose.Result The mortality rate,similar to that in L-ornithine-L-aspartate therapy(25%),in L-ornithine-L-aspartate combined with lactulose treatment was 21.7%,much lower than that in aceglutamide treatment group(47.1%,P0.05).Conclusion L-ornithine-L-aspartate combined with lactulose in the treatment of patients with hepatic encephalopathy can effectively decrease the mortality rate.

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Available abstract

Aim To explore the effect of L-ornithine-L-aspartate combined with lactulose in the treatment of patients with hepatic encephalopathy after hepatic cirrhosis.Methods 68 patients with hepatic encephalopathy were selected and 17 patients received treatment of aceglutamide,28 patients received treatment of L-ornithine-L-aspartate and other 23 L-ornithine-L-aspartate combined with lactulose.Result The mortality rate,similar to that in L-ornithine-L-aspartate therapy(25%),in L-ornithine-L-aspartate combined with lactulose treatment was 21.7%,much lower than that in aceglutamide treatment group(47.1%,P0.05).Conclusion L-ornithine-L-aspartate combined with lactulose in the treatment of patients with hepatic encephalopathy can effectively decrease the mortality rate.

Key concepts: Lactulose, Hepatic encephalopathy, Gastroenterology, Cirrhosis, Ornithine, Internal medicine, Medicine, Encephalopathy

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Effect of L-ornithine-L-aspartate combined with lactulose in the treatment of patients with hepatic encephalopathy after hepatic cirrhosis — Research Paper | ScholarLens