Recent Advance in Determination Methods of Melamine in Foods and Animal Feeds

Melamine is a small polar triazine compound. Due to its rich in nitrogen, it has been added to give a false impression of high protein content. Melamine added to food and animal feeds could possibly cause fatal kidney stones. Determination of melamine is therefore of large importance to ensure food safety. This article reviewed the modern methods of sample preparation and determination of melamine in foods and animal feeds including high-performance liquid chromatography, gas chromatogra-phy-mass spectrometry, high-performance liquid chromatography-mass spectrometry and enzyme-linked immunosorbent assay.