Comparative Analysis of Mammographic Findings and Pathological Features of Phyllodes Tumor of Breast

Objective To investigate the mammographic appearance of breast phyllodes tumors and the relationship of mammographic appearance to clinicopathologic features,and to determine the differential characteristics and pathologic basis.Methods The clinical and imaging findings of 28 patients with surgically confirmed phyllodes tumors from January 2010 to January 2013 were analyzed retrospectively.The radiological features were compared with pathology.Results Seventeen benign,8 intermediate,and 3 malignant phyllodes tumors were identified by the histopathologic review.Mammography demonstrated the tumors as a mass lesion in 26 cases and asymmetric opacity in 2 cases.The tumors were 2.8-10.2 cm in diameter.The difference of rate of intermediate and malignant phyllodes tumors and benign phyllodes tumors was not statistically significant between ≥3 cm and 3 cm in diameter(Ρ0.05).Although all the tumors showed lobulated margins except for 4 cases in the benign phyllodes tumors,it was not a significant finding(Ρ0.05).However,poorly defined borders in the malignant and intermediate phyllodes tumors were more frequent than those in the benign phyllodes tumors(Ρ0.05).Abnormal blood vessels were seen in 2 cases of benign phyllodes tumors and calcification was seen in 1 case of benign phyllodes tumors,while 10 tumors were surrounded by a clear halo,of them 8 were the benign phyllodes tumors and 2 were the intermediate and malignant phyllodes tumors(Ρ 0.05).Conclusions Mammographic features combined with clinical behavior can be helpful for early detection,but definite diagnosis and classification should be verified by histopathologic examination.