Analysis on thickness of retinal nerve fiber layer in myopia by using optical conhenrence tomography

Objective To study the characteristics and clinical significance of retinal nerve fiber layer (RNFL)thickness along with an increase of myopia degree.Methods According to the myopic degree,150 subjects were divided into 4 groups:normal,slight,medium and high myopic groups.Optical conhenrence tomography(OCT)was used to measure the RNFL thickness.Each subject had circular scans aroud the optic nerve with a circle size of 3.46mm.The mean and different quadrants RNFL thickness in different groups were analyzed.Results Compared with normal groups,the mean RNFL thickness in myopic groups were thinner,but only high myopic groups were significantly thinner.The change occurred first in nasal quadrant.RNFL thickness in high myopic groups were significantly thinner in nasal,inferior and superior quadrant.However,temporal quadrant was significantly thicker.ConcIusion The mean RNFL thickness in myopic groups are thinner and thinner along with an increase of myopia degree.Different from others, temporal quadrant is thicker,which maybe characteristics of RNFL thickness in myopic groups.Above- mentioned features have the clinical significance for diagnosing disease.