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Icariin enhances the proliferation of human gingival fibroblasts in vitro

Jin Li

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Abstract

Objective To investigate the effects of icariin on the proliferation of the human gingival fibroblasts (HGF).Methods HGF were cultured in vitro and stimulated with icariin with three concentrations (0.001,0.01,0.1μg/ml) for 0,24,48,72 and 96 hours.The ability of proliferation of HGF was detected by MTT method.Results The proliferation of HGF were enhanced by icariin ( P0.01),and the most efficient concentration was 0.01 μg/ml.Conclusions Icariin may up regulate the proliferation of HGF.

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What this paper is about

Objective To investigate the effects of icariin on the proliferation of the human gingival fibroblasts (HGF).Methods HGF were cultured in vitro and stimulated with icariin with three concentrations (0.001,0.01,0.1μg/ml) for 0,24,48,72 and 96 hours.The ability of proliferation of HGF was detected by MTT method.Results The proliferation of HGF were enhanced by icariin ( P0.01),and the most efficient concentration was 0.01 μg/ml.Conclusions Icariin may up regulate the proliferation of HGF.

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Available abstract

Objective To investigate the effects of icariin on the proliferation of the human gingival fibroblasts (HGF).Methods HGF were cultured in vitro and stimulated with icariin with three concentrations (0.001,0.01,0.1μg/ml) for 0,24,48,72 and 96 hours.The ability of proliferation of HGF was detected by MTT method.Results The proliferation of HGF were enhanced by icariin ( P0.01),and the most efficient concentration was 0.01 μg/ml.Conclusions Icariin may up regulate the proliferation of HGF.

Key concepts: Icariin, In vitro, Chemistry, MTT assay, Internal medicine, Molecular biology, Biology, Medicine

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