ScholarLens Back to search
2003•Unpublished venueRequires access

Changes of serum insulin-like growth factor-1 levels in patients with essential hypertension

Xiao-yang Pei

Open publisher page 0 citations

Abstract

Objective: To investigate the changes of serum insulin-like growth factor-1 (IGF-1) levels in patients with essential hypertension (EH) and assess the pathophysiologic significance of IGF-1 in hypertension patients with left ventricular hypertrophy (LVH) . Methods: Serum IGF-1 levels were measured by specific radioimmunoassay in 50 EH patients and in 25 normotensive controls. Results: The results showed that serum IGF-1 level were higher in EH than normal controls (12. 86 ± 3. 67 vs 9. 67±2. 57, P0. 01) . The IGF-1 Serum level were higher in EH with LVH than in those without LVH (14. 15 ± 4. 23 vs 11. 57 ± 3. 10, P0. 01) . Conclusion: These results indicate that serum IGF-1 levels are increased in essential hypertension, especially in EH with LVH.It also suggest that IGF-1 may involve hypertension and hypertensive cardiac hypertrophy.

About this research paper

What this paper is about

Objective: To investigate the changes of serum insulin-like growth factor-1 (IGF-1) levels in patients with essential hypertension (EH) and assess the pathophysiologic significance of IGF-1 in hypertension patients with left ventricular hypertrophy (LVH) . Methods: Serum IGF-1 levels were measured by specific radioimmunoassay in 50 EH patients and in 25 normotensive controls. Results: The results showed that serum IGF-1 level were higher in EH than normal controls (12. 86 ± 3. 67 vs 9. 67±2. 57, P0. 01) . The IGF-1 Serum level were higher in EH with LVH than in those without LVH (14. 15 ± 4. 23 vs 11. 57 ± 3. 10, P0. 01) . Conclusion: These results indicate that serum IGF-1 levels are increased in essential hypertension, especially in EH with LVH.It also suggest that IGF-1 may involve hypertension and hypertensive cardiac hypertrophy.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective: To investigate the changes of serum insulin-like growth factor-1 (IGF-1) levels in patients with essential hypertension (EH) and assess the pathophysiologic significance of IGF-1 in hypertension patients with left ventricular hypertrophy (LVH) . Methods: Serum IGF-1 levels were measured by specific radioimmunoassay in 50 EH patients and in 25 normotensive controls. Results: The results showed that serum IGF-1 level were higher in EH than normal controls (12. 86 ± 3. 67 vs 9. 67±2. 57, P0. 01) . The IGF-1 Serum level were higher in EH with LVH than in those without LVH (14. 15 ± 4. 23 vs 11. 57 ± 3. 10, P0. 01) . Conclusion: These results indicate that serum IGF-1 levels are increased in essential hypertension, especially in EH with LVH.It also suggest that IGF-1 may involve hypertension and hypertensive cardiac hypertrophy.

Key concepts: Medicine, Essential hypertension, Internal medicine, Left ventricular hypertrophy, Endocrinology, Radioimmunoassay, Pathophysiology, Insulin-like growth factor

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Changes of serum insulin-like growth factor-1 levels in patients with essential hypertension — Research Paper | ScholarLens