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THE CLINICAL SIGNIFICANCE OF SERUM LEVELS OF NITROGEN TERMINAL BRAIN NATRIURETIC PEPTIDE(NT-BNP) IN THE DIAGNOSIS OF NON-TYPICAL HEART FAILURE

Shuxian Zhou

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Abstract

Objective To find out the clinical value of serum level of nitrogen terminal brain natriuretic peptide(NT-BNP) in the diagnosis of old non-typical heart failure patients and its advantages compared with the ultrasonic cardiograph(UCG).Methods Sixty patients received both NT-BNP test and echocardiography examination.A statistical analysis was used to analyze the relationship between these items. Results The serum levels of NT-BNP were significantly different between chronic heart failure(CHF) group and non-CHF group(t=13.19,P0.001).NT-BNP had higher sensitivity than left ventricle ejection fraction(LVEF) when NT-BNP450 ng/L(u=4.22,P0.01). Conclusion NT-BNP is a quantitative index in the diagnosis and differential diagnosis of CHF.Compared with UCG,NT-BNP showed higher sensitivity and negative predictive value in the diagnosis of CHF.

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Objective To find out the clinical value of serum level of nitrogen terminal brain natriuretic peptide(NT-BNP) in the diagnosis of old non-typical heart failure patients and its advantages compared with the ultrasonic cardiograph(UCG).Methods Sixty patients received both NT-BNP test and echocardiography examination.A statistical analysis was used to analyze the relationship between these items. Results The serum levels of NT-BNP were significantly different between chronic heart failure(CHF) group and non-CHF group(t=13.19,P0.001).NT-BNP had higher sensitivity than left ventricle ejection fraction(LVEF) when NT-BNP450 ng/L(u=4.22,P0.01). Conclusion NT-BNP is a quantitative index in the diagnosis and differential diagnosis of CHF.Compared with UCG,NT-BNP showed higher sensitivity and negative predictive value in the diagnosis of CHF.

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Available abstract

Objective To find out the clinical value of serum level of nitrogen terminal brain natriuretic peptide(NT-BNP) in the diagnosis of old non-typical heart failure patients and its advantages compared with the ultrasonic cardiograph(UCG).Methods Sixty patients received both NT-BNP test and echocardiography examination.A statistical analysis was used to analyze the relationship between these items. Results The serum levels of NT-BNP were significantly different between chronic heart failure(CHF) group and non-CHF group(t=13.19,P0.001).NT-BNP had higher sensitivity than left ventricle ejection fraction(LVEF) when NT-BNP450 ng/L(u=4.22,P0.01). Conclusion NT-BNP is a quantitative index in the diagnosis and differential diagnosis of CHF.Compared with UCG,NT-BNP showed higher sensitivity and negative predictive value in the diagnosis of CHF.

Key concepts: Heart failure, Ejection fraction, Internal medicine, Medicine, Ventricle, Cardiology, N-terminal pro-Brain Natriuretic Peptide, Brain natriuretic peptide

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THE CLINICAL SIGNIFICANCE OF SERUM LEVELS OF NITROGEN TERMINAL BRAIN NATRIURETIC PEPTIDE(NT-BNP) IN THE DIAGNOSIS OF NON-TYPICAL HEART FAILURE — Research Paper | ScholarLens