2009Zhongguo laonianxue zazhiRequires access

Effect of minimally invasive hematoma stereotactic aspiration therapy on serum neuron specific enolase in cerebral hemorrhage

Chen Li

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Abstract

Objective To investigate effect of minimally invasive hematoma stereotactic aspiration therapy on serum neuron specific enolase (NSE) in cerebral hemorrhage. Methods Hematoma volume, Zea Longa score and serum NSE level were detected. Results Compared with control group, hematoma volume, signals of neurological functional deficit score and serum NSE level had obvious difference in treatment group on the third and 7th day (P0.05, P0.001). Serum NSE level had positive correlation not only with hematoma volume also with prognosis. Conclusions Early minimally invasive hematoma stereotactic aspiration therapy can decrease hematoma volume and NSE level obviously and improve prognosis, which suggest NSE would be a reliable index to predict early neurological functional deficit and recovery.

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What this paper is about

Objective To investigate effect of minimally invasive hematoma stereotactic aspiration therapy on serum neuron specific enolase (NSE) in cerebral hemorrhage. Methods Hematoma volume, Zea Longa score and serum NSE level were detected. Results Compared with control group, hematoma volume, signals of neurological functional deficit score and serum NSE level had obvious difference in treatment group on the third and 7th day (P0.05, P0.001). Serum NSE level had positive correlation not only with hematoma volume also with prognosis. Conclusions Early minimally invasive hematoma stereotactic aspiration therapy can decrease hematoma volume and NSE level obviously and improve prognosis, which suggest NSE would be a reliable index to predict early neurological functional deficit and recovery.

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Available abstract

Objective To investigate effect of minimally invasive hematoma stereotactic aspiration therapy on serum neuron specific enolase (NSE) in cerebral hemorrhage. Methods Hematoma volume, Zea Longa score and serum NSE level were detected. Results Compared with control group, hematoma volume, signals of neurological functional deficit score and serum NSE level had obvious difference in treatment group on the third and 7th day (P0.05, P0.001). Serum NSE level had positive correlation not only with hematoma volume also with prognosis. Conclusions Early minimally invasive hematoma stereotactic aspiration therapy can decrease hematoma volume and NSE level obviously and improve prognosis, which suggest NSE would be a reliable index to predict early neurological functional deficit and recovery.

Key concepts: Enolase, Hematoma, Medicine, Intracranial hematoma, Anesthesia, Surgery, Internal medicine, Immunohistochemistry

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