Photoselective vaporization of prostate for the treatment of benign prostatic hyperplasia

Objective To evaluate the safety and efficacy of photoselective vaporization of prostate (PVP) for the treatment of benign prostatic hyperplasia (BPH). Methods A total of 161 patients with symptomatic bladder outlet obstruction due to BPH underwent PVP via transurethral with Niagara PV TM system.The therapeutic results were assessed using following variables:the safety and efficacy of sacral anesthesia,blood loss,operative time,indwelling catheterization,mean Qmax,IPSS,QOL and the sexual function. Results The PVP was successfully performed on all the 161 patients with BPH.There were 160 patients under sacral anesthesia and only 1 under epidural anesthesia.The mean operative time was (44.5±22.4)min (range,15～210 min).All patients had minimal or no blood loss and no patients required blood transfusion.No postoperative catheterization was needed in 21 patients. The mean catheterization time was (34.4± 20.8 )h (range,24-72 h).Postoperatively 2 cases had transient dysuria and 2 experienced delayed hematuria.All cases were followed up for 3 to 6 months after treatment.The mean Qmax increased from (6.5± 2.4 )ml/s to (19.8±2.1)ml/s;mean IPSS and QOL decreased to 5.8±1.6 and 1.7±0.4,respectively,which showed significant improvement,compared with those before operation( P 0.05).The 49 cases with sexual function still remained potent postoperatively.All patients were satisfied with voiding outcome and had no postoperative incontinence. Conclusions The PVP is an excellent treatment modality for BPH.It can yield rapid, safe and effective relief for patients with obstructive BPH with minimal invasion,especially for those at advanced age or at high risk.