Distribution and Drug Resistance of 632 Isolates of Enterococcus

Objective To analyze the distribution and drug resistance of enterococcus to the common antibiotics,to guide rational application of antibiotics for clinic.Methods The bacteria were identified by Phoneix 100 system,the antimicrobial susceptibility was evaluated by disk diffusion test.Results 632 strains were isolated from clinical specimens,including 403 strains of Enterococcus faecalis(63.7%),166 strains of Enterococcus faecium(26.3%),49 strains of Enterococcus avium(7.8%),14 strains of Enterococcus durans(2.2%).The strains were mainly isolated from sputa(36.2%) and urine(21.3%).Enterococcus exhibited the highest resistance to erythromycin.The next resistant drugs were rifampin,levofloxacin,ciprofloxacin successively.As a whole, the resistant rate of Enterococcus faecium was higher than Enterococcus faecalis.During this study,5 strains of vancomycin resistant and 2 strains of linezolid resistant were detected in Enterococcus faecalis,while not founded in other enterococcus.Conclusion In view of the obvious difference in the distribution and drug resistance of enterococcus,the clinical treatment should be rational according to susceptibility test results.Moreover,with the existing of vancomycin and linezolid resistant enterococcus,our clinician should pay more attention.