Effect of smoking on the male sperm morphology,sperm DNA integrity rate and sperm acrosome integrity rate

Objective To study the effect of smoking on male sperm morphology,sperm DNA integrity rate[DNA fragmentation index( DFI) was used for the evaluating]and acrosome integrity rate. Methods A retrospective analysis was performed on 1 500 male patients come to our center for treatment( 1 300 smokers and 200 non-smokers). According to the daily smoking quantity the patients were divided into A1 group( 500 cases) : 20 / day,A2group( 600 cases) : 10 ~ 20 / day,A3 group( 200 cases) : 1 ~ 9 / day; and group B( 200 cases) : 0 / day( as the control group). Results The normal morphology rate of sperm decreased with the increase of daily smoking quantity,the pair comparison showed a significant differences between groups( P 0. 05); the rate of sperm DNA integrity decreased with the rise of smoking( DFI will be increase),the pair comparison showed a significant differences between groups( P 0. 05); the sperm acrosome integrity rate decreased with the increase of smoking quantity,the pair comparison showed a significant differences between groups( P 0. 05). Conclusion With the increase of daily smoking quantity the rate of normal sperm morphology,sperm DNA integrity rate and sperm acrosome integrity rate are reduced,and is not good for male reproductive health.