Clinic observation on the a-lb therapy for patients with hand,foot and mouth disease

OBJECTIVE To evaluate the efficacy of interferon a-lb On treating children with hand,foot and mouth disease.METHODS 256 children with hand,foot and mouth disease were randomly divided into two groups,and the therapy group had 118 cases,which were received interferon(Hapgen)by injection one time per day.The control group had 138 cases which were given ribavirin by intravenous or injection one time per day for 3 days.RESULTS The total effective rates of therapy group was 96.62%.While that of control group was 60.15%.There was significant difference between two groups(P﹤0.01).Therapy group was better than control group in temperature decreasing and curing the skin rash and mouth ulcer.No side effect had been found in therapy group.CONCLUSION Efficacy of interferon a-lb is better than ribavirin,which is worthy of application.