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2004•Journal of Medical ForumRequires access

Study of vWF、GMP-140 in Patients with B-CS

LI Linpeng

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Abstract

Objective To explore the clinical and pathophysiologyic significance of change of plasma vWF、GMP-140 in patients with B-CS. Methods vWF,GMP-140 were detected in 60 patients with B-CS and 30 controls using enzyme-linked immunosirbent assay(ELISA).Results The level of vWF GMP-140 were significantly increased in B-CS comparison with controls(P0.01),Moreover,there was no significant correlation between the vWF or GMP-140 and the platelet count in B-CS(r=-0.164 and -0.0369 ,P0.05) .Conclusion High quantity of vWF GMP-140 in patients with B-CS suggest that the hypercoagulable state of B-CS may be mainly caused by the increase of vWF、 GMP-140.

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Objective To explore the clinical and pathophysiologyic significance of change of plasma vWF、GMP-140 in patients with B-CS. Methods vWF,GMP-140 were detected in 60 patients with B-CS and 30 controls using enzyme-linked immunosirbent assay(ELISA).Results The level of vWF GMP-140 were significantly increased in B-CS comparison with controls(P0.01),Moreover,there was no significant correlation between the vWF or GMP-140 and the platelet count in B-CS(r=-0.164 and -0.0369 ,P0.05) .Conclusion High quantity of vWF GMP-140 in patients with B-CS suggest that the hypercoagulable state of B-CS may be mainly caused by the increase of vWF、 GMP-140.

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Available abstract

Objective To explore the clinical and pathophysiologyic significance of change of plasma vWF、GMP-140 in patients with B-CS. Methods vWF,GMP-140 were detected in 60 patients with B-CS and 30 controls using enzyme-linked immunosirbent assay(ELISA).Results The level of vWF GMP-140 were significantly increased in B-CS comparison with controls(P0.01),Moreover,there was no significant correlation between the vWF or GMP-140 and the platelet count in B-CS(r=-0.164 and -0.0369 ,P0.05) .Conclusion High quantity of vWF GMP-140 in patients with B-CS suggest that the hypercoagulable state of B-CS may be mainly caused by the increase of vWF、 GMP-140.

Key concepts: Platelet, Von Willebrand factor, Internal medicine, Medicine, Chemistry, Plasma levels, Endocrinology, Immunology

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