2001•Chinese Journal of PharmaceuticalsRequires access

Relative Bioavailability of Tramadol Hydrochloride Sustained Release Tablets

Yu Hu

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Abstract

A HPLC method was used for determination of tramadol hydrochloride in human serum. The relative bioavailability of two brands of tramadol hydrochloride sustained release tablets was studied in healthy volunteers. The results showed there was no statistically significant difference for pharmacokinetic parameters between the two bioequivalent preparations.

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What this paper is about

A HPLC method was used for determination of tramadol hydrochloride in human serum. The relative bioavailability of two brands of tramadol hydrochloride sustained release tablets was studied in healthy volunteers. The results showed there was no statistically significant difference for pharmacokinetic parameters between the two bioequivalent preparations.

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Available abstract

A HPLC method was used for determination of tramadol hydrochloride in human serum. The relative bioavailability of two brands of tramadol hydrochloride sustained release tablets was studied in healthy volunteers. The results showed there was no statistically significant difference for pharmacokinetic parameters between the two bioequivalent preparations.

Key concepts: Bioavailability, Tramadol Hydrochloride, Bioequivalence, Chemistry, Pharmacokinetics, Pharmacology, Tramadol, Chromatography

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