Changes of PSA level in prostatic fluid of the patients with chronic prostatitis

Objective To determine the changes of prostate specific antigen (PSA) in prostate fluid of the patients with chronic prostatitis to investigate the diagnostic implication of PSA in chronie prostatitis. Methods Fifty five patients with chronic prostatitis (experimental group) and 11 patients with other urological diseases (control group) underwent prostate fluid routine examination, bacterial culture and PSA level determination. Results PSA level in prostate fluid of the experimental group was significantly higher than in the control group ( P 0.01). But PSA had no obvious difference between bacterial and nonbacterial infection subgroups. Between experimental and control groups the examination of lecithin bodies showed a significant difference ( P 0.01). The correlation coefficient of PSA and leukocyte count in the experimental group was r =0.2 ( P 0.04). Conclusion PSA in prostatic fluid could be increased in chronic prostatitis and could be used as an indicator to diagnose the chronic prostatitis.