The relationship between PSA density and histologically proven chronic prostatitis.

Aim: Prostate-specific antigen (PSA) may elevate in case of prostate cancer, benign prostatic hyperplasia (BPH) as well as chronic prostatitis. In chronic prostatitis and BPH distinction PSA, free / total PSA ratio isn’t usefull. The aim of this study is to question the place of PSA density in the distinction of BPH and prostatitis. Materials and Methods: In our clinic BPH pre - diagnosed, data of transurethral resection of prostate (TUR-P) performed and histologically diagnosed as no chronic prostatitis observed (group 1), with TUR-P performed but chronic prostatitis diagnosed (group 2) patients were retrospectively analyzed. The age, PSA, biopsy history, prostate size and PSA density (PSAD = PSA level / prostate volume) of patients were recorded. Results: Chronic prostatitis was determined in 100 of 641 patients (15.6%). Biopsy before TUR-P was performed to 28 patients in the chronic prostatitis group, and 27 patients in BPH group (n=100) and in only 4 patients (14.3%) in the chronic prostatitis group pathological evidence of prostatitis was determined. PSA (p