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Analysis of 174 Adverse Drug Reactions Reports in Our Hospital

Wenli Xie

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Abstract

OBJECTIVE: To investigate the characteristics and regularity of adverse drug reaction (ADR) in our hospital. METHODS: 174 ADR cases in our hospital reported to state ADR monitoring center were analyzed in respect of patients’ sex and age, route of administration, reporting source, type of drugs, organ and system involved in ADR and its clinical symptom, etc. RESULTS: Among 174 ADR cases, 53 patients aged over 60 years accounted for 30.46%. 137 cases were induced by intravenous dripping injection (78.74%). 108 cases were induced by anti-infective drugs (62.07%). The main clinical manifestations of ADR were lesions of skin and its appendants in 81 cases (46.56%). CONCLUSION: The medical organization should pay close attention to ADR reporting and monitoring, especially anti-infective drugs and drugs for injection, so as to prevent and reduce the occurrence of ADR.

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What this paper is about

OBJECTIVE: To investigate the characteristics and regularity of adverse drug reaction (ADR) in our hospital. METHODS: 174 ADR cases in our hospital reported to state ADR monitoring center were analyzed in respect of patients’ sex and age, route of administration, reporting source, type of drugs, organ and system involved in ADR and its clinical symptom, etc. RESULTS: Among 174 ADR cases, 53 patients aged over 60 years accounted for 30.46%. 137 cases were induced by intravenous dripping injection (78.74%). 108 cases were induced by anti-infective drugs (62.07%). The main clinical manifestations of ADR were lesions of skin and its appendants in 81 cases (46.56%). CONCLUSION: The medical organization should pay close attention to ADR reporting and monitoring, especially anti-infective drugs and drugs for injection, so as to prevent and reduce the occurrence of ADR.

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Available abstract

OBJECTIVE: To investigate the characteristics and regularity of adverse drug reaction (ADR) in our hospital. METHODS: 174 ADR cases in our hospital reported to state ADR monitoring center were analyzed in respect of patients’ sex and age, route of administration, reporting source, type of drugs, organ and system involved in ADR and its clinical symptom, etc. RESULTS: Among 174 ADR cases, 53 patients aged over 60 years accounted for 30.46%. 137 cases were induced by intravenous dripping injection (78.74%). 108 cases were induced by anti-infective drugs (62.07%). The main clinical manifestations of ADR were lesions of skin and its appendants in 81 cases (46.56%). CONCLUSION: The medical organization should pay close attention to ADR reporting and monitoring, especially anti-infective drugs and drugs for injection, so as to prevent and reduce the occurrence of ADR.

Key concepts: Medicine, Drug reaction, Adverse drug reaction, Drug, Route of administration, Intravenous route, Adverse effect, Internal medicine

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