2009Yiyao daobaoRequires access

Evaluation of Eye Irritation of Labrosol in Rabbits

Yuan Zhang

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Abstract

Objective To explore the eye irritation of Labrasol in different concentrations in rabbits and determine its safety extent. Methods Use Draize's scale to investigate the eye irritation of Labrasol in rabbits. Results It was found that Labrasol at concentrations of 0.5%,1.0%,1.5%,2.0% and 3.0% showed no eye irritations, while mild irritation at 5.0%. Conclusion The safety range of labrasol in an eye preparation was 0.5% to 3.0%.

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What this paper is about

Objective To explore the eye irritation of Labrasol in different concentrations in rabbits and determine its safety extent. Methods Use Draize's scale to investigate the eye irritation of Labrasol in rabbits. Results It was found that Labrasol at concentrations of 0.5%,1.0%,1.5%,2.0% and 3.0% showed no eye irritations, while mild irritation at 5.0%. Conclusion The safety range of labrasol in an eye preparation was 0.5% to 3.0%.

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Available abstract

Objective To explore the eye irritation of Labrasol in different concentrations in rabbits and determine its safety extent. Methods Use Draize's scale to investigate the eye irritation of Labrasol in rabbits. Results It was found that Labrasol at concentrations of 0.5%,1.0%,1.5%,2.0% and 3.0% showed no eye irritations, while mild irritation at 5.0%. Conclusion The safety range of labrasol in an eye preparation was 0.5% to 3.0%.

Key concepts: Eye irritation, Irritation, Skin irritation, Medicine, Ophthalmology, Pharmacology, Dermatology, Immunology

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