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The study of immunology changes of varicocele in children

WU Rongde

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Abstract

Objective To understand the immune function of the children with varicocele (VC) and provide reference data for the male infertility. Methods After the peripheral vein blood were taken from 17 children (aged from 9～12 years) with VC, T lymphocyte subgroup, immunoglobulin, complements and RBC immunity were detected, while 17 healthy boys with the same age were selected at random as the control group. Results The immune values of the children with VC were lower than that of the control group. Especially, the T lymphocyte subgroup and immunoglobulin had significant statistic difference. Conclusion The immune function of the children with VC is reduced, which may be one of the reasons that destroyed the blood-testis barrier.

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What this paper is about

Objective To understand the immune function of the children with varicocele (VC) and provide reference data for the male infertility. Methods After the peripheral vein blood were taken from 17 children (aged from 9～12 years) with VC, T lymphocyte subgroup, immunoglobulin, complements and RBC immunity were detected, while 17 healthy boys with the same age were selected at random as the control group. Results The immune values of the children with VC were lower than that of the control group. Especially, the T lymphocyte subgroup and immunoglobulin had significant statistic difference. Conclusion The immune function of the children with VC is reduced, which may be one of the reasons that destroyed the blood-testis barrier.

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Available abstract

Objective To understand the immune function of the children with varicocele (VC) and provide reference data for the male infertility. Methods After the peripheral vein blood were taken from 17 children (aged from 9～12 years) with VC, T lymphocyte subgroup, immunoglobulin, complements and RBC immunity were detected, while 17 healthy boys with the same age were selected at random as the control group. Results The immune values of the children with VC were lower than that of the control group. Especially, the T lymphocyte subgroup and immunoglobulin had significant statistic difference. Conclusion The immune function of the children with VC is reduced, which may be one of the reasons that destroyed the blood-testis barrier.

Key concepts: Medicine, Varicocele, Immune system, Lymphocyte subsets, Lymphocyte, Antibody, Immunology, Infertility

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